Lytic versus stimulatory synapse in cytotoxic T lymphocyte/target cell interaction: manifestation of a dual activation threshold.

Activation of biological functions in T lymphocytes is determined by the molecular dynamics occurring at the T cell/opposing cell interface. In the present study, a central question of cytotoxic T lymphocyte (CTL) biology was studied at the single-cell level: can two distinct activation thresholds f...

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Bibliographic Details
Main Authors: Faroudi, M, Utzny, C, Salio, M, Cerundolo, V, Guiraud, M, Müller, S, Valitutti, S
Format: Journal article
Language:English
Published: 2003