The superhelical TPR-repeat domain of O-linked GlcNAc transferase exhibits structural similarities to importin alpha.

Addition of N-acetylglucosamine (GlcNAc) is a ubiquitous form of intracellular glycosylation catalyzed by the conserved O-linked GlcNAc transferase (OGT). OGT contains an N-terminal domain of tetratricopeptide (TPR) repeats that mediates the recognition of a broad range of target proteins. Component...

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Hlavní autoři: Jínek, M, Rehwinkel, J, Lazarus, B, Izaurralde, E, Hanover, J, Conti, E
Médium: Journal article
Jazyk:English
Vydáno: 2004