IkappaB genetic polymorphisms and invasive pneumococcal disease.

RATIONALE: Increasing evidence supports a key role for the transcription factor nuclear factor (NF)-kappaB in the host response to pneumococcal infection. Control of NF-kappaB activity is achieved through interactions with the IkappaB family of inhibitors, encoded by the genes NFKBIA, NFKBIB, and NF...

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Bibliographic Details
Main Authors: Chapman, S, Khor, C, Vannberg, F, Frodsham, A, Walley, A, Maskell, N, Davies, C, Segal, S, Moore, C, Gillespie, S, Denny, P, Day, N, Crook, D, Davies, R, Hill, A
Format: Journal article
Language:English
Published: 2007