Structurally sophisticated octahedral metal complexes as highly selective protein kinase inhibitors.

The generation of synthetic compounds with exclusive target specificity is an extraordinary challenge of molecular recognition and demands novel design strategies, in particular for large and homologous protein families such as protein kinases with more than 500 members. Simple organic molecules oft...

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Bibliografiske detaljer
Main Authors: Feng, L, Geisselbrecht, Y, Blanck, S, Wilbuer, A, Atilla-Gokcumen, G, Filippakopoulos, P, Kräling, K, Celik, M, Harms, K, Maksimoska, J, Marmorstein, R, Frenking, G, Knapp, S, Essen, L, Meggers, E
Format: Journal article
Sprog:English
Udgivet: 2011