Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms.

Dissociable deficits in the decision-making cognition of chronic amphetamine abusers, opiate abusers, patients with focal damage to prefrontal cortex, and tryptophan-depleted normal volunteers: evidence for monoaminergic mechanisms.

We used a novel computerized decision-making task to compare the decision-making behavior of chronic amphetamine abusers, chronic opiate abusers, and patients with focal lesions of orbital prefrontal cortex (PFC) or dorsolateral/medial PFC. We also assessed the effects of reducing central 5-hydroxyt...

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Detalles Bibliográficos
Main Authors: Rogers, R, Everitt, B, Baldacchino, A, Blackshaw, A, Swainson, R, Wynne, K, Baker, N, Hunter, J, Carthy, T, Booker, E, London, M, Deakin, J, Sahakian, B, Robbins, T
Formato: Journal article
Idioma:English
Publicado: 1999

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