Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs
Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...
Κύριοι συγγραφείς: | Larrouture, Q, Cribbs, A, Rao, S, Philpott, M, Snelling, S, Knowles, H |
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Μορφή: | Journal article |
Γλώσσα: | English |
Έκδοση: |
Springer Nature
2021
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Παρόμοια τεκμήρια
Παρόμοια τεκμήρια
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Osteoclasts are multinucleated cells that degrade cartilage as well as bone
ανά: Larrouture, Q, κ.ά.
Έκδοση: (2018) -
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
ανά: Larrouture, QC
Έκδοση: (2019) -
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
ανά: Henrik Löfvall, κ.ά.
Έκδοση: (2018-04-01) -
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation
ανά: Doo Ri Park, κ.ά.
Έκδοση: (2020-08-01) -
Chondroclasts are mature osteoclasts which are capable of cartilage matrix resorption
ανά: Knowles, H, κ.ά.
Έκδοση: (2012)