Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair.
In a chronically hypoxic tissue such as cartilage, adaptations to hypoxia do not merely include cell survival responses, but also promotion of its specific function. This review will focus on describing such hypoxia-mediated chondrocyte function, in particular in the permanent articular cartilage. T...
المؤلفون الرئيسيون: | Murphy, C, Thoms, B, Vaghjiani, R, Lafont, J |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2009
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مواد مشابهة
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HIFs in human articular chondrocytes
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Promotion of chondrocyte function by inhibition of HIF-specific hydroxylases
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Hypoxia promotes the production and inhibits the destruction of human articular cartilage.
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منشور في: (2013) -
Promotion of the chondrocyte phenotype by the inhibition of HIF-specific proyl-hydroxylase domain (PHD) enzymes
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Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype.
حسب: Lafont, J, وآخرون
منشور في: (2007)