Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair.
In a chronically hypoxic tissue such as cartilage, adaptations to hypoxia do not merely include cell survival responses, but also promotion of its specific function. This review will focus on describing such hypoxia-mediated chondrocyte function, in particular in the permanent articular cartilage. T...
Autori principali: | Murphy, C, Thoms, B, Vaghjiani, R, Lafont, J |
---|---|
Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2009
|
Documenti analoghi
-
HIFs in human articular chondrocytes
di: Lafont, J, et al.
Pubblicazione: (2009) -
Promotion of chondrocyte function by inhibition of HIF-specific hydroxylases
di: Thoms, B, et al.
Pubblicazione: (2010) -
Hypoxia promotes the production and inhibits the destruction of human articular cartilage.
di: Thoms, B, et al.
Pubblicazione: (2013) -
Promotion of the chondrocyte phenotype by the inhibition of HIF-specific proyl-hydroxylase domain (PHD) enzymes
di: Thoms, B, et al.
Pubblicazione: (2009) -
Hypoxia-inducible factor 2alpha is essential for hypoxic induction of the human articular chondrocyte phenotype.
di: Lafont, J, et al.
Pubblicazione: (2007)