Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis.

Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis.

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Ankylosing spondylitis (AS) is a common and highly familial rheumatic disorder. The sibling recurrence risk ratio for the disease is 63 and heritability assessed in twins >90%. Although MHC genes, including HLA-B27, contribute only 20-50% of the genetic risk for the disease, no non-MHC gene h...

書目詳細資料
Main Authors:	Brown, M, Edwards, S, Hoyle, E, Campbell, S, Laval, S, Daly, A, Pile, K, Calin, A, Ebringer, A, Weeks, D, Wordsworth, B
格式:	Journal article
語言:	English
出版:	2000

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