Roles of quaternary architectures in immunoglobulin glycosylation and antibody-based therapeutics

<p>Immunoglobulins play a key role in humoral immunity and have emerged as an important class of biotherapeutics. While the IgG1 backbone tends to be the conventional choice in these recombinant therapies, several therapeutics that focus on other immunoglobulin isotypes are being developed.<...

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Bibliographic Details
Main Author: Le, N
Other Authors: Zitzmann, N
Format: Thesis
Language:English
Published: 2018