The three methyls: the function and therapeutic potential of histone H3K36 trimethylation

<p>DNA is wrapped around proteins called histones, whose modification regulates numerous cellular processes. Therefore it is not surprising that mutations in the genes that modify the histones are frequently associated with human cancer. For example, mutations in <em>SETD2</em>, en...

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Bibliographic Details
Main Author: Pfister, SX
Other Authors: Humphrey, T
Format: Thesis
Language:English
Published: 2014
Subjects: