Linkage disequilibrium and age of HLA region SNPs in relation to classic HLA gene alleles within Europe.

The HLA region on chromosome 6 is gene-rich and under selective pressure because of the high proportion of immunity-related genes. Linkage disequilibrium (LD) patterns and allele frequencies in this region are highly differentiated across broad geographical populations, making it a region of interes...

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Autors principals: Evseeva, I, Nicodemus, K, Bonilla, C, Tonks, S, Bodmer, W
Format: Journal article
Idioma:English
Publicat: 2010