Synthesis of heterocycle-substituted bicyclo[3.1.1]heptanes and aza-bicyclo[3.1.1]heptanes via photocatalytic minisci reaction

A route toward heterocycle-functionalized bicyclo[3.1.1]heptanes (BCHeps) and aza-bicyclo[3.1.1]heptanes (aza-BCHeps) has been developed, using mild, photocatalytic Minisci-like conditions to introduce various heterocycles at the bridgehead position from readily available N-hydroxyphthalimide esters...

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Príomhchruthaitheoirí: Revie, RI, Whitaker, BJ, Paul, B, Smith, RC, Anderson, EA
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: American Chemical Society 2024