Chronic relapsing homologous collagen-induced arthritis in DBA/1 mice as a model for testing disease-modifying and remission-inducing therapies.

OBJECTIVE: To test whether the chronic relapsing arthritis induced by immunizing DBA/1 mice with homologous type II collagen is a valuable model for testing disease-modifying antiarthritic drugs. METHODS: Six-week-old male DBA/1 mice were immunized with murine type II collagen in Freund's compl...

Full description

Bibliographic Details
Main Authors: Malfait, A, Williams, R, Malik, A, Maini, R, Feldmann, M
Format: Journal article
Language:English
Published: 2001