FGF signalling restricts haematopoietic stem cell specification via modulation of the BMP pathway.
Haematopoietic stem cells (HSCs) are produced during embryogenesis from the floor of the dorsal aorta. The localization of HSCs is dependent on the presence of instructive signals on the ventral side of the vessel. The nature of the extrinsic molecular signals that control the aortic haematopoietic...
| Main Authors: | , , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2014
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