Antibody–antigen complex modelling in the era of immunoglobulin repertoire sequencing

The natural immune repertoire can be a useful guide to antibody discovery against any given target. However, the large volume of immunoglobulin gene sequencing data necessitates the rational prioritisation of possible binders for experimental validation. Where other known binders exist, sequence sim...

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Detalles Bibliográficos
Autores principales: Raybould, M, Wong, W, Deane, C
Formato: Journal article
Lenguaje:English
Publicado: Royal Society of Chemistry 2019