Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes a...
Главные авторы: | Verra, F, Simpore, J, Warimwe, G, Tetteh, K, Howard, T, Osier, F, Bancone, G, Avellino, P, Blot, I, Fegan, G, Bull, P, Williams, T, Conway, D, Marsh, K, Modiano, D |
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Формат: | Journal article |
Язык: | English |
Опубликовано: |
Public Library of Science
2007
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