Cation-controlled enantioselective and diastereoselective synthesis of indolines: an autoinductive phase-transfer initiated 5-endo-trig process

A catalytic enantioselective approach to the synthesis of indolines bearing two asymmetric centers, one of which is all-carbon and quaternary, is described. This reaction proceeds with high levels of diastereoselectivity (>20:1) and high levels of enantioselectivity (up to 99.5:0.5 er) in t...

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Bibliographic Details
Main Authors: Sharma, K, Wolstenhulme, J, Painter, P, Yeo, D, Grande-Carmona, F, Johnston, C, Tantillo, D, Smith, M
Format: Journal article
Language:eng
Published: American Chemical Society 2015