Biodistribution and pharmacokinetic studies of a porphyrin dimer photosensitizer (Oxdime) by fluorescence imaging and spectroscopy in mice bearing xenograft tumors.

Biodistribution and pharmacokinetic studies of a porphyrin dimer photosensitizer (Oxdime) by fluorescence imaging and spectroscopy in mice bearing xenograft tumors.

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Herein, we present a study of the pharmacokinetics and biodistribution of a butadiyne-linked conjugated porphyrin dimer (Oxdime) designed to have high near-infrared (NIR) 2-photon absorption cross-section for photodynamic therapy (PDT). Changes in biodistribution over time were monitored in mice car...

Полное описание

Библиографические подробности
Главные авторы:	Khurana, M, Ulrich, S, Kim, A, Moriyama, Y, Netchev, G, Akens, M, Anderson, H, Wilson, B
Формат:	Journal article
Язык:	English
Опубликовано:	2012

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