Adrenergic stimulation of the human pituitary-adrenal axis is attenuated by an analog of met-enkephalin.

It has previously been suggested that endogenous opioid peptides may suppress the pituitary-adrenal axis in man by inhibiting an excitatory alpha 1-adrenoceptor input to neural mechanisms liberating corticotrophin-releasing factor or factors (CRFs). This hypothesis has been tested here by investigat...

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Bibliographic Details
Main Authors: Delitala, G, Palermo, M, Tomasi, P, Besser, M, Grossman, A
Format: Journal article
Language:English
Published: 1991