Small heat shock protein activity is regulated by variable oligomeric substructure

The alpha-crystallins are members of the small heat shock protein family of molecular chaperones that have evolved to minimize intracellular protein aggregation; however, they are also implicated in a number of protein deposition diseases. In this study, we employed novel mass spectrometry technique...

Full description

Bibliographic Details
Main Authors: Benesch, J, Ayoub, M, Robinson, C, al., E
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2008