Fine-mapping identifies multiple prostate cancer risk loci at 5p15, one of which associates with TERT expression.

Associations between single nucleotide polymorphisms (SNPs) at 5p15 and multiple cancer types have been reported. We have previously shown evidence for a strong association between prostate cancer (PrCa) risk and rs2242652 at 5p15, intronic in the telomerase reverse transcriptase (TERT) gene that en...

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Main Authors: Kote-Jarai, Z, Saunders, E, Leongamornlert, D, Tymrakiewicz, M, Dadaev, T, Jugurnauth-Little, S, Ross-Adams, H, Al Olama, A, Benlloch, S, Halim, S, Russell, R, Russel, R, Dunning, A, Luccarini, C, Dennis, J, Neal, D, Hamdy, F, Donovan, J, Muir, K, Giles, G, Severi, G, Wiklund, F, Gronberg, H, Haiman, C, Schumacher, F, Henderson, B, Le Marchand, L, Lindstrom, S, Kraft, P, Hunter, D, Gapstur, S, Chanock, S, Berndt, S, Albanes, D, Andriole, G, Schleutker, J, Weischer, M, Canzian, F, Riboli, E, Key, T, Travis, R, Campa, D, Ingles, SA, John, E, Hayes, R, Pharoah, P, Khaw, K, Stanford, J, Ostrander, E, Signorello, L, Thibodeau, SN, Schaid, D, Maier, C, Vogel, W, Kibel, A, Cybulski, C, Lubinski, J, Cannon-Albright, L, Brenner, H, Park, J, Kaneva, R, Batra, J, Spurdle, A, Clements, J, Teixeira, MR, Govindasami, K, Guy, M, Wilkinson, R, Sawyer, E, Morgan, A, Dicks, E, Baynes, C, Conroy, D, Bojesen, SE, Kaaks, R, Vincent, D, Bacot, F, Tessier, D, Easton, D, Eeles, R
Format: Journal article
Language:English
Published: Oxford University Press 2013