Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound.

Oncolytic viruses (OV) and ultrasound-enhanced drug delivery are powerful novel technologies. OV selectively self-amplify and kill cancer cells but their clinical use has been restricted by limited delivery from the bloodstream into the tumor. Ultrasound has been previously exploited for targeted re...

Full description

Bibliographic Details
Main Authors: Bazan-Peregrino, M, Rifai, B, Carlisle, R, Choi, J, Arvanitis, C, Seymour, L, Coussios, C
Format: Journal article
Language:English
Published: 2013