Expanding chemical biology of 2-oxoglutarate oxygenases.

Beyond established roles in collagen biosynthesis, hypoxic signaling and fatty acid metabolism, recent reports have now revealed roles for human 2-oxoglutarate-dependent oxygenases in histone and nucleic acid demethylation and in signaling protein hydroxylation. The emerging role of these oxygenases...

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Detalhes bibliográficos
Principais autores: Loenarz, C, Schofield, C
Formato: Journal article
Idioma:English
Publicado em: 2008