Expanding chemical biology of 2-oxoglutarate oxygenases.

Beyond established roles in collagen biosynthesis, hypoxic signaling and fatty acid metabolism, recent reports have now revealed roles for human 2-oxoglutarate-dependent oxygenases in histone and nucleic acid demethylation and in signaling protein hydroxylation. The emerging role of these oxygenases...

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Bibliographic Details
Main Authors: Loenarz, C, Schofield, C
Format: Journal article
Language:English
Published: 2008