Immune evasion in malaria: altered peptide ligands of the circumsporozoite protein.

T cells are central to immunity in malaria. CD4+ helper T cells favour the generation of high-affinity antibodies that are effective against blood stages and they are necessary to establish immunological memory. The intrahepatic stage of infection can be eliminated by specific CD8+ cytotoxic T cells...

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Bibliographic Details
Main Authors: Plebanski, M, Lee, E, Hill, A
Format: Journal article
Language:English
Published: 1997