Large-scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E ε2/ε3/ε4 genotype

Results from two small studies, involving a total of only 174 cases, have suggested that the increased risk of coronary heart disease conferred by cigarette smoking is substantially affected by genotype at the apolipoprotein E (APOE) ε2/ε3/ε4 polymorphism. We have established APOE genotypes in 4484...

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Bibliographic Details
Main Authors: Keavney, B, Parish, S, Palmer, A, Clark, S, Youngman, L, Danesh, J, McKenzie, C, Delépine, M, Lathrop, M, Peto, R, Collins, R
Format: Journal article
Language:English
Published: 2003