Contribution of proteasome-catalyzed peptide cis-splicing to viral targeting by CD8+ T cells in HIV-1 infection

Peptides generated by proteasome-catalyzed splicing of noncontiguous amino acid sequences have been shown to constitute a source of nontemplated human leukocyte antigen class I (HLA-I) epitopes, but their role in pathogen-specific immunity remains unknown. CD8+ T cells are key mediators of HIV type...

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Bibliographic Details
Main Authors: Paes, W, Leonov, G, Partridge, T, Frangou, A, Brackenridge, S, Nicastri, A, Parker, R, McMichael, A, Ternette, N, Borrow, P
Format: Journal article
Published: National Academy of Sciences 2019