Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.

In vitro studies suggest that the G protein-coupled receptor (GPR) 30 is a functional estrogen receptor. However, the physiological role of GPR30 in vivo is unknown, and it remains to be determined whether GPR30 is an estrogen receptor also in vivo. To this end, we studied the effects of disrupting...

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Bibliographic Details
Main Authors:	Mårtensson, U, Salehi, SA, Windahl, S, Gomez, M, Swärd, K, Daszkiewicz-Nilsson, J, Wendt, A, Andersson, N, Hellstrand, P, Grände, P, Owman, C, Rosen, C, Adamo, M, Lundquist, I, Rorsman, P, Nilsson, B, Ohlsson, C, Olde, B, Leeb-Lundberg, L
Format:	Journal article
Language:	English
Published:	2009

Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.

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