Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers.
One of the current challenges in gene therapy is to construct a vector that will target specific tissues. Targeting expression to endothelium is of particular interest in the treatment of several pathologies. We have shown previously that defined regions of the E-selectin and KDR promoters confer en...
Автори: | , , |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
2000
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