Increasing endothelial cell specific expression by the use of heterologous hypoxic and cytokine-inducible enhancers.

One of the current challenges in gene therapy is to construct a vector that will target specific tissues. Targeting expression to endothelium is of particular interest in the treatment of several pathologies. We have shown previously that defined regions of the E-selectin and KDR promoters confer en...

Повний опис

Бібліографічні деталі
Автори: Modlich, U, Pugh, C, Bicknell, R
Формат: Journal article
Мова:English
Опубліковано: 2000