Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation
Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.
Hauptverfasser: | , , |
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Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2001
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