Linear fluorescent oligonucleotide probes with an acridine quencher generate a signal upon hybridisation

Linear, single stranded probes incorporating a fluorophore and an acridine moiety are weakly fluorescent until hybridised to a complementary target nucleic acid whereupon fluorescence increases due to reduced quenching.

Bibliographic Details
Main Authors: Ranasinghe, RT, Brown, L, Brown, T
Format: Journal article
Language:English
Published: 2001