Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications

Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxia-inducible factor (HIF) isoforms. Synthetic hypox...

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Bibliographic Details
Main Authors: Hsu, K-F, Wilkins, S, Hopkinson, R, Sekirnik, R, Flashman, E, Kawamura, A, McCullagh, J, Walport, L, Schofield, C
Format: Journal article
Language:English
Published: Taylor & Francis 2020