Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications

Post-translational modifications (PTMs) to the tails of the core histone proteins are critically involved in epigenetic regulation. Hypoxia affects histone modifications by altering the activities of histone-modifying enzymes and the levels of hypoxia-inducible factor (HIF) isoforms. Synthetic hypox...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Hsu, K-F, Wilkins, S, Hopkinson, R, Sekirnik, R, Flashman, E, Kawamura, A, McCullagh, J, Walport, L, Schofield, C
التنسيق:	Journal article
اللغة:	English
منشور في:	Taylor & Francis 2020

مواد مشابهة

Hypoxia and hypoxia mimetics differentially modulate histone post-translational modifications
حسب: Kuo-Feng Hsu, وآخرون
منشور في: (2021-01-01)

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.
حسب: Sánchez-Fernández, E, وآخرون
منشور في: (2013)

Mechanisms of human histone and nucleic acid demethylases
حسب: Walport, L, وآخرون
منشور في: (2012)

Mechanisms of human histone and nucleic acid demethylases.
حسب: Walport, L, وآخرون
منشور في: (2012)

Investigating the contribution of the active site environment to the slow reaction of hypoxia-inducible factor prolyl hydroxylase domain 2 with oxygen.
حسب: Tarhonskaya, H, وآخرون
منشور في: (2014)

Hypoxia Mimetic Agents for Ischemic Stroke
حسب: Charles K. Davis, وآخرون
منشور في: (2019-01-01)

Histone deacetylase 8 protects human proximal tubular epithelial cells from hypoxia-mimetic cobalt- and hypoxia/reoxygenation-induced mitochondrial fission and cytotoxicity
حسب: Soon-Duck Ha, وآخرون
منشور في: (2018-07-01)

Kinetic investigations on the reaction of a 2-oxoglutarate dependent histone demethylase with oxygen
حسب: Sanchez-Fernandez, E, وآخرون
منشور في: (2012)

Hypoxia mimetics restore bone biomineralisation in hyperglycaemic environments
حسب: Azadeh Rezaei, وآخرون
منشور في: (2022-08-01)

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases.
حسب: Walport, L, وآخرون
منشور في: (2016)

Roles of Post-Translational Modifications of Transcription Factors Involved in Breast Cancer Hypoxia
حسب: Logan Seymour, وآخرون
منشور في: (2025-02-01)

Substrate selectivity analyses of factor inhibiting hypoxia-inducible factor.
حسب: Yang, M, وآخرون
منشور في: (2013)

The Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT/HIF-1β) is Influenced by Hypoxia and Hypoxia-Mimetics
حسب: Matthias Wolff, وآخرون
منشور في: (2013-09-01)

The biological effect of cobalt chloride mimetic-hypoxia on nucleus pulposus cells and the comparability with physical hypoxia in vitro
حسب: Xiao-Xin Gao, وآخرون
منشور في: (2021-10-01)

Mechanistic and structural studies of KDM‐catalysed demethylation of histone 1 isotype 4 at lysine 26
حسب: Walport, L, وآخرون
منشور في: (2018)

Synthetic post-translational modification of histones
حسب: Nadal, S, وآخرون
منشور في: (2018)

Lysine-241 has a role in coupling 2OG turnover with substrate oxidation during KDM4-catalysed histone demethylation
حسب: Hancock, R, وآخرون
منشور في: (2018)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
حسب: Flashman, E, وآخرون
منشور في: (2010)

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen.
حسب: Flashman, E, وآخرون
منشور في: (2010)

Editorial: The Development of New Classes of Hypoxia Mimetic Agents for Clinical Use
حسب: Ruoli Chen, وآخرون
منشور في: (2019-06-01)

Human histone demethylase KDM6B can catalyse sequential oxidations
حسب: Hopkinson, R, وآخرون
منشور في: (2018)

Hypoxia induces alterations in tRNA modifications involved in translational control
حسب: Huanping Guo, وآخرون
منشور في: (2023-02-01)

Hypoxia-induced down-regulation of neprilysin by histone modification in mouse primary cortical and hippocampal neurons.
حسب: Zheng Wang, وآخرون
منشور في: (2011-04-01)

Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
حسب: Louise J. Walport, وآخرون
منشور في: (2016-06-01)

Conserved N-terminal cysteine dioxygenases transduce responses to hypoxia in animals and plants
حسب: Masson, N, وآخرون
منشور في: (2019)

Investigating the dependence of the hypoxia-inducible factor hydroxylases (factor inhibiting HIF and prolyl hydroxylase domain 2) on ascorbate and other reducing agents.
حسب: Flashman, E, وآخرون
منشور في: (2010)

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases.
حسب: Chowdhury, R, وآخرون
منشور في: (2009)

Studies on the activity of the hypoxia-inducible-factor hydroxylases using an oxygen consumption assay.
حسب: Ehrismann, D, وآخرون
منشور في: (2007)

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.
حسب: Pollard, P, وآخرون
منشور في: (2008)

Recent progress in histone demethylase inhibitors
حسب: McAllister, T, وآخرون
منشور في: (2016)

Inhibition of the oxygen-sensing asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor: a potential hypoxia response modulating strategy
حسب: Wu, Y, وآخرون
منشور في: (2021)

mRNA-to-protein translation in hypoxia
حسب: Nancy T. Chee, وآخرون
منشور في: (2019-03-01)

Signalling hypoxia by HIF hydroxylases.
حسب: Schofield, C, وآخرون
منشور في: (2005)

The histone deacetylase inhibitor, Vorinostat, represses hypoxia inducible factor 1 alpha expression through translational inhibition.
حسب: Darren M Hutt, وآخرون
منشور في: (2014-01-01)

Conversion of cysteine into dehydroalanine enables access to synthetic histones bearing diverse post-translational modifications.
حسب: Chalker, J, وآخرون
منشور في: (2012)

Targeting histone lysine demethylases - Progress, challenges, and the future.
حسب: Thinnes, C, وآخرون
منشور في: (2014)

2-oxoglutarate regulates binding of hydroxylated hypoxia-inducible factor to prolyl hydroxylase domain 2
حسب: Abboud, M, وآخرون
منشور في: (2018)

Histone post-translational modification and the DNA damage response
حسب: Haoyun Song, وآخرون
منشور في: (2023-07-01)

Histones, Their Variants and Post-translational Modifications in Zebrafish Development
حسب: Vincenzo Cavalieri, وآخرون
منشور في: (2020-06-01)

Role of Histone Post-Translational Modifications in Inflammatory Diseases
حسب: Yingying Lin, وآخرون
منشور في: (2022-02-01)