Adaptations to Maintain Energy Homeostasis Compensate for Creatine-Deficiency in GAMT Knockout Mice Following Myocardial Infarction, but May Contribute to Early Mitochondrial Pathology During Aging

Míreanna comhchosúla

• Hearts from gamt ko mice lack phospho-creatine, show reduced inotropic reserve and are more prone to ischemia
  de réir: ten Hove, M, et al.
  Foilsithe / Cruthaithe: (2005)
• Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction.
  de réir: Lygate, C, et al.
  Foilsithe / Cruthaithe: (2012)
• COMPENSATION FOR IMPAIRED MYOCARDIAL PHOSPHOTRANSFER IN GUANIDINOACETATE-N-METHYLTRANSFERASE KNOCKOUT MICE
  de réir: Aksentijevic, D, et al.
  Foilsithe / Cruthaithe: (2010)
• Regulation of Myocardial Creatine Uptake by Intra- and Extracellular Creatine Levels
  de réir: Makinen, K, et al.
  Foilsithe / Cruthaithe: (2008)
• Elevated Myocardial Creatine Protects Against Ischemia/Reperfusion Injury by Improving Cardiac Energetics
  de réir: Lygate, C, et al.
  Foilsithe / Cruthaithe: (2011)