Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure.
BACKGROUND: Elevated plasma norepinephrine levels are associated with increased mortality in patients and in animal models with chronic heart failure. To test which alpha2-adrenoceptor subtypes operate as presynaptic inhibitory receptors to control norepinephrine release in heart failure, we invest...
Main Authors: | Brede, M, Wiesmann, F, Jahns, R, Hadamek, K, Arnolt, C, Neubauer, S, Lohse, M, Hein, L |
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Format: | Journal article |
Language: | English |
Published: |
2002
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