Structure of the Fanconi anaemia monoubiquitin ligase complex

The Fanconi anaemia (FA) pathway repairs DNA damage caused by endogenous and chemotherapy-induced DNA crosslinks, and responds to replication stress1,2. Genetic inactivation of this pathway by mutation of genes encoding FA complementation group (FANC) proteins impairs development, prevents blood pro...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Shakeel, S, Rajendra, E, Alcón, P, O'Reilly, F, Chorev, D, Maslen, S, Degliesposti, G, Russo, C, He, S, Hill, C, Skehel, J, Scheres, S, Patel, K, Rappsilber, J, Robinson, C, Passmore, L
Μορφή: Journal article
Γλώσσα:English
Έκδοση: Nature Research 2019