Molecular basis for redox control by the human cystine/glutamate antiporter system xc−
Cysteine plays an essential role in cellular redox homoeostasis as a key constituent of the tripeptide glutathione (GSH). A rate limiting step in cellular GSH synthesis is the availability of cysteine. However, circulating cysteine exists in the blood as the oxidised di-peptide cystine, requiring sp...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2021
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