Commentary. A picture of Mitf in melanoma immortality.
The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senesce...
المؤلف الرئيسي: | |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2011
|