Commentary. A picture of Mitf in melanoma immortality.

The Mitf gene has a key role in melanocytes and melanoma by regulating cell cycle progression, survival and differentiation. Two papers in this issue of Oncogene (Cheli et al., 2011; Strub et al., 2011) reveal that low-Mitf cells can initiate tumors with high efficiency, and that Mitf blocks senesce...

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Glavni avtor: Goding, C
Format: Journal article
Jezik:English
Izdano: 2011