Characterisation of the innate immune sensor MDA5
<p>Melanoma Differentiation-Associated gene 5 (MDA5) is a cytosolic RNA receptor. Its activation triggers the production of the antiviral cytokines type I and III Interferons (IFN). It is believed that MDA5 detects viral and/or cellular RNAs. The latter case may be relevant in the context o...
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| Format: | Thesis |
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2017
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