$Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.$

Presence of multiple recurrent mutations confers poor trial outcome of relapsed/refractory CLL.

Although TP53, NOTCH1, and SF3B1 mutations may impair prognosis of patients with chronic lymphocytic leukemia (CLL) receiving frontline therapy, the impact of these mutations or any other, alone or in combination, remains unclear at relapse. The genome of 114 relapsed/refractory patients included in...

書誌詳細
主要な著者:	Guièze, R, Robbe, P, Clifford, R, de Guibert, S, Pereira, B, Timbs, A, Dilhuydy, M, Cabes, M, Ysebaert, L, Burns, A, Nguyen-Khac, F, Davi, F, Véronèse, L, Combes, P, Le Garff-Tavernier, M, Leblond, V, Merle-Béral, H, Alsolami, R, Hamblin, A, Mason, J, Pettitt, A, Hillmen, P, Taylor, J, Knight, S, Tournilhac, O, Schuh, A
フォーマット:	Journal article
言語:	English
出版事項:	American Society of Hematology 2015

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