Epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa.
Epistatic interactions between resistance mutations in antibiotic-free environments potentially play a crucial role in the spread of resistance in pathogen populations by determining the fitness cost associated with resistance. We used an experimental evolution approach to test for epistatic interac...
| Główni autorzy: | , |
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| Format: | Journal article |
| Język: | English |
| Wydane: |
2011
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