Epistasis buffers the fitness effects of rifampicin- resistance mutations in Pseudomonas aeruginosa.
Epistatic interactions between resistance mutations in antibiotic-free environments potentially play a crucial role in the spread of resistance in pathogen populations by determining the fitness cost associated with resistance. We used an experimental evolution approach to test for epistatic interac...
Автори: | , |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
2011
|