Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.

Atrial sources of reactive oxygen species vary with the duration and substrate of atrial fibrillation: implications for the antiarrhythmic effect of statins.

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BACKGROUND: An altered nitric oxide-redox balance has been implicated in the pathogenesis of atrial fibrillation (AF). Statins inhibit NOX2-NADPH oxidases and prevent postoperative AF but are less effective in AF secondary prevention; the mechanisms underlying these findings are poorly understood. M...

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Библиографические подробности
Главные авторы:	Reilly, SN, Jayaram, R, Nahar, K, Antoniades, C, Verheule, S, Channon, K, Alp, N, Schotten, U, Casadei, B
Формат:	Journal article
Язык:	English
Опубликовано:	2011

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