BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma
Whether cell types exposed to a high level of environmental insults possess cell type-specific prosurvival mechanisms or enhanced DNA damage repair capacity is not well understood. BRN2 is a tissue-restricted POU domain transcription factor implicated in neural development and several cancers. In me...
Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Journal article |
Published: |
Cold Spring Harbor Laboratory Press
2019
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