Decreased plasma tryptophan concentration in major depression: relationship to melancholia and weight loss.

Plasma total tryptophan (TRP) concentration was significantly lower in 31 patients with major depression compared to a healthy control group. The ratio of plasma TRP concentration to that of other branch chain amino acids (the TRP:BCAA ratio) was also decreased. Further analysis revealed that the de...

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Bibliographic Details
Main Authors: Anderson, I, Parry-Billings, M, Newsholme, E, Poortmans, JR, Cowen, P
Format: Journal article
Language:English
Published: 1990