DM loss in k haplotype mice reveals isotype-specific chaperone requirements.

DM actions as a class II chaperone promote capture of diverse peptides inside the endocytic compartment(s). DM mutant cells studied to date express class II bound by class II-associated invariant chain-derived peptide (CLIP), a short proteolytic fragment of the invariant chain, and exhibit defective...

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Bibliographic Details
Main Authors: Koonce, C, Wutz, G, Robertson, E, Vogt, AB, Kropshofer, H, Bikoff, E
Format: Journal article
Language:English
Published: 2003