Delivery of oligonucleotide‐based therapeutics: challenges and opportunities

Nucleic acid‐based therapeutics that regulate gene expression have been developed towards clinical use at a steady pace for several decades, but in recent years the field has been accelerating. To date, there are 11 marketed products based on antisense oligonucleotides, aptamers and small interferin...

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Bibliographic Details
Main Authors: Hammond, SM, Aartsma‐Rus, A, Alves, S, Borgos, SE, Buijsen, RAM, Collin, RWJ, Covello, G, Denti, MA, Desviat, LR, Echevarría, L, Foged, C, Gaina, G, Garanto, A, Goyenvalle, AT, Guzowska, M, Holodnuka, I, Jones, DR, Krause, S, Lehto, T, Montolio, M, Van Roon‐Mom, W, Arechavala‐Gomeza, V
Format: Journal article
Language:English
Published: Springer 2021