Identifying causal mechanisms for beta cell dysfunction at type 2 diabetes risk loci
<p>Genome-wide association studies (GWAS) have identified more than 150 loci associated with type 2 diabetes (T2D) risk. Most association signals are located in noncoding regions of the genome, and uncertainty remains over the causal gene in the vast majority of cases. Motivated by the overall...
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| Format: | Thesis |
| Language: | English |
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2017
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