Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but only to a minority of cancer patients. The current priority is to understand why the majority of patients fail to respond. Besides T-cell dysfunction, T-cell apoptosis was reported in several recent studies a...

書誌詳細
主要な著者:	Zhu, J, Petit, P, Van Den Eynde, B
フォーマット:	Journal article
言語:	English
出版事項:	Springer Berlin Heidelberg 2018

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