Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Apoptosis of tumor-infiltrating T lymphocytes: a new immune checkpoint mechanism

Immunotherapy based on checkpoint inhibitors is providing substantial clinical benefit, but only to a minority of cancer patients. The current priority is to understand why the majority of patients fail to respond. Besides T-cell dysfunction, T-cell apoptosis was reported in several recent studies a...

書誌詳細
主要な著者:	Zhu, J, Petit, P, Van Den Eynde, B
フォーマット:	Journal article
言語:	English
出版事項:	Springer Berlin Heidelberg 2018

類似資料

Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes
著者:: Zhu, J, 等
出版事項: (2017)

Prognostic relevance of tumor-infiltrating lymphocytes and immune checkpoints in pediatric medulloblastoma
著者:: Jeroen F. Vermeulen, 等
出版事項: (2018-03-01)

Infiltrating T lymphocytes and tumor microenvironment within cholangiocarcinoma: immune heterogeneity, intercellular communication, immune checkpoints
著者:: Yunyan Dai, 等
出版事項: (2025-01-01)

Immune checkpoint therapy responders display early clonal expansion of tumor infiltrating lymphocytes
著者:: Joel Kidman, 等
出版事項: (2024-12-01)

Tumor-infiltrating lymphocytes and immune-related adverse events in advanced melanoma
著者:: I.A.J. van Duin, 等
出版事項: (2024-12-01)

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
著者:: Finisguerra, V, 等
出版事項: (2023)

Checkpoint molecules on infiltrating immune cells in colorectal tumor microenvironment
著者:: Iman M. Talaat, 等
出版事項: (2022-08-01)

Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression
著者:: Benoit J Van den Eynde, 等
出版事項: (2023-05-01)

Expression of immune checkpoints (PD-L1 and IDO) and tumour-infiltrating lymphocytes in breast cancer
著者:: Noura Alkhayyal, 等
出版事項: (2022-09-01)

Anti-metabolite chemotherapy increases LAG-3 expressing tumor-infiltrating lymphocytes which can be targeted by combination immune checkpoint blockade
著者:: Elly Marcq, 等
出版事項: (2024-09-01)

Overexpression of an Immune Checkpoint (CD155) in Breast Cancer Associated with Prognostic Significance and Exhausted Tumor-Infiltrating Lymphocytes: A Cohort Study
著者:: Yu-Chen Li, 等
出版事項: (2020-01-01)

Tryptophan-degrading enzymes in tumoral immune resistance
著者:: Nicolas van Baren, 等
出版事項: (2016-11-01)

Immune infiltrate populations within distinct tumor immune microenvironments predictive of immune checkpoint treatment outcome
著者:: Brian Z Ring, 等
出版事項: (2025-01-01)

Dissecting tumor lymphocyte infiltration to predict benefit from immune-checkpoint inhibitors in metastatic colorectal cancer: lessons from the AtezoT RIBE study
著者:: Chiara Cremolini, 等
出版事項: (2023-04-01)

Characterization of Immune Cell Subsets of Tumor Infiltrating Lymphocytes in Brain Metastases
著者:: Priyakshi Kalita-de Croft, 等
出版事項: (2021-05-01)

POLE and Mismatch Repair Status, Checkpoint Proteins and Tumor-Infiltrating Lymphocytes in Combination, and Tumor Differentiation: Identify Endometrial Cancers for Immunotherapy
著者:: Dandan Dong, 等
出版事項: (2021-03-01)

WAYS TO ENHANCE LYMPHOCYTE TRAFFICKING INTO TUMORS AND FITNESS OF TUMOR INFILTRATING LYMPHOCYTES
著者:: Matteo eBellone, 等
出版事項: (2013-09-01)

Tumor-infiltrating lymphocytes for melanoma immunotherapy
著者:: Oliver Kepp, 等
出版事項: (2023-12-01)

The role of tumor-infiltrating lymphocytes in cholangiocarcinoma
著者:: Dong Liu, 等
出版事項: (2022-04-01)

Role of tumor-infiltrating lymphocytes in melanoma
著者:: Yasemin Benderli Cihan
出版事項: (2019-01-01)

Influence of Tumor Immune Infiltration on Immune Checkpoint Inhibitor Therapeutic Efficacy: A Computational Retrospective Study
著者:: Rong Liu, 等
出版事項: (2021-06-01)

PD-L1 Expression and Tumor Infiltrating Lymphocytes in Neurofibromatosis Type 1-Related Benign Tumors and Malignant Peripheral Nerve Sheath Tumors: An Implication for Immune Checkpoint Inhibition Therapy
著者:: Jin LIU, 等
出版事項: (2021-06-01)

177 Treatment outcomes with unselected autologous tumor infiltrating lymphocytes in patients with checkpoint inhibition–refractory advanced cutaneous melanoma
著者:: Natalia Kirillova, 等
出版事項: (2021-11-01)

Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy
著者:: McAuliffe, J, 等
出版事項: (2021)

Adoptive transfer of tumor-infiltrating lymphocytes in melanoma: a viable treatment option
著者:: Maartje W. Rohaan, 等
出版事項: (2018-10-01)

Marsdenia tenacissima enhances immune response of tumor infiltrating T lymphocytes to colorectal cancer
著者:: Ben Yi, 等
出版事項: (2023-08-01)

Tumor-Infiltrating Lymphocytes in Triple Negative Breast Cancer: The Future of Immune Targeting
著者:: Paula García-Teijido, 等
出版事項: (2016-04-01)

Tumor-Infiltrating Lymphocytes in Triple Negative Breast Cancer: The Future of Immune Targeting
著者:: Paula García-Teijido, 等
出版事項: (2016-01-01)

Immunity and cancer: role of tumor-infiltrating lymphocytes in triple-negative breast cancer
著者:: Ana Tečić-Vuger, 等
出版事項: (2021-01-01)

T lymphocyte-targeted immune checkpoint modulation in glioma
著者:: Mark Gilbert, 等
出版事項: (2020-05-01)

Perspectives of tumor-infiltrating lymphocyte treatment in solid tumors
著者:: Shuhang Wang, 等
出版事項: (2021-06-01)

1306 Negative selection of ligand-receptor interactions mediating lymphocyte infiltration confers melanoma resistance to immune checkpoint blockade therapy by turning hot tumors to cold
著者:: Binbin Wang, 等
出版事項: (2023-11-01)

Pretreatment neutrophil-to-lymphocyte ratio and mutational burden as biomarkers of tumor response to immune checkpoint inhibitors
著者:: Cristina Valero, 等
出版事項: (2021-02-01)

MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltration
著者:: Jianheng Peng, 等
出版事項: (2023-06-01)

Tumor-infiltrating immune cell status predicts successful response to immune checkpoint inhibitors in renal cell carcinoma
著者:: Akira Kazama, 等
出版事項: (2022-11-01)

Combined Assessment of the Tumor–Stroma Ratio and Tumor Immune Cell Infiltrate for Immune Checkpoint Inhibitor Therapy Response Prediction in Colon Cancer
著者:: Cor J. Ravensbergen, 等
出版事項: (2021-10-01)

Immune Checkpoints in Circulating and Tumor-Infiltrating CD4+ T Cell Subsets in Colorectal Cancer Patients
著者:: Salman M. Toor, 等
出版事項: (2019-12-01)

Arid5a: A missing link between EMT and tumoral immune resistance
著者:: Van den Eynde, BJ
出版事項: (2021)

Heterologous prime-boost vaccination targeting MAGE-type antigens promotes tumor T-cell infiltration and improves checkpoint blockade therapy
著者:: Federica Cappuccini, 等
出版事項: (2021-09-01)

Advances and prospects in tumor infiltrating lymphocyte therapy
著者:: Xu Qiu, 等
出版事項: (2024-11-01)